Fmoc-N-Me-Phe-OH is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amino group during the synthesis process. The N-methylation of the phenylalanine residue introduces steric hindrance, which can be beneficial in designing peptides with specific conformational properties or enhanced metabolic stability. This compound is especially valuable in the synthesis of modified peptides for pharmaceutical research, where N-methylation can improve bioavailability and resistance to enzymatic degradation. Additionally, it is utilized in the development of peptidomimetics and bioactive peptides for therapeutic applications, such as enzyme inhibitors or receptor ligands.