Used in biomedical research to measure levels of cAMP response element-binding protein (CREB) in human samples. Helps assess CREB activation in signaling pathways linked to memory, cell survival, and gene expression. Commonly applied in neuroscience, cancer, and metabolic disease studies. Enables high-throughput screening of drug effects on intracellular signaling. Provides quantitative data from cell lysates, tissue extracts, or serum samples. Supports investigation of phosphorylated and total CREB forms to understand pathway dynamics.