Used in biomedical research to detect and quantify mouse type IV collagen in tissue extracts, serum, or cell culture samples. Helps assess basement membrane integrity and remodeling in studies related to fibrosis, cancer, kidney disease, and liver injury. Commonly applied in preclinical models to monitor disease progression or evaluate therapeutic interventions targeting extracellular matrix changes. Provides a sensitive and specific measurement method suitable for high-throughput analysis in immunology, oncology, and toxicology research.