Used in biomedical research to measure cyclooxygenase-1 (COX-1) levels in rat samples, this ELISA kit enables accurate quantification of COX-1 protein expression in tissues or cell lysates. It is commonly applied in studies related to inflammation, pain, and fever, where COX-1 plays a role in prostaglandin synthesis. Researchers use it to evaluate the effects of drugs, especially nonsteroidal anti-inflammatory drugs (NSAIDs), on COX-1 activity, helping to distinguish between COX-1 and COX-2 inhibition. The kit supports investigation into gastrointestinal, renal, and cardiovascular functions in rat models, where COX-1 has constitutive regulatory roles. It is also useful in toxicology studies assessing drug-induced tissue damage.