Used in biomedical research to quantify Claudin-1 protein levels in cell or tissue samples. Helps study tight junction integrity and epithelial barrier function. Commonly applied in research on skin diseases, liver disorders, and cancer progression. Enables assessment of Claudin-1 expression changes in response to drugs or inflammatory stimuli. Supports investigation into viral entry mechanisms, as Claudin-1 acts as a co-receptor for hepatitis C virus. Widely used in preclinical studies to evaluate therapeutic targets involving epithelial permeability and cell adhesion.