Used in epigenetic research to quantitatively measure DNMT3B protein levels in mouse tissue or cell lysates. Helps investigate DNA methylation patterns during development, genomic imprinting, and X-chromosome inactivation. Widely applied in studies of cancer biology, stem cell differentiation, and neurological disorders where aberrant DNA methylation is implicated. Enables researchers to assess changes in DNMT3B expression under experimental conditions such as drug treatment, gene knockout, or disease models. Provides a reliable, high-throughput method for monitoring epigenetic enzyme activity without requiring radioactive materials.