Used in biomedical research to quantify levels of HYOU1 protein in cell lysates, tissue extracts, and biological fluids. Enables investigation of cellular stress responses, particularly under hypoxic conditions associated with cancer, ischemic diseases, and neurodegenerative disorders. Supports studies on endoplasmic reticulum stress and unfolded protein response pathways. Facilitates biomarker discovery and evaluation of therapeutic interventions targeting hypoxia-related mechanisms.