Used in biomedical research to quantify levels of Human Type I Collagen Alpha 2 Chain in tissue samples, cell cultures, or biological fluids. Helps assess extracellular matrix formation, tissue remodeling, and fibrosis progression in conditions like liver cirrhosis, pulmonary fibrosis, and scleroderma. Supports studies in wound healing, bone regeneration, and connective tissue disorders by providing a reliable measure of collagen expression. Commonly applied in preclinical drug development to evaluate anti-fibrotic therapies and monitor treatment efficacy.