Used in biomedical research to measure osteocalcin levels in biological samples such as serum or plasma. Helps assess bone formation and turnover in studies related to osteoporosis, metabolic bone diseases, and fracture risk. Commonly applied in clinical labs and research settings to evaluate osteoblast activity and monitor responses to bone-targeted therapies. Also used in endocrine research due to osteocalcin’s role in glucose metabolism and insulin regulation.