Used in biomedical research to quantify levels of PGC-1α protein in human tissue samples, particularly in studies related to mitochondrial biogenesis, energy metabolism, and oxidative stress. Commonly applied in investigating metabolic disorders such as type 2 diabetes, obesity, and insulin resistance. Also utilized in exercise physiology research to assess changes in PGC-1α expression following physical activity. Supports analysis in neurodegenerative disease studies, including Parkinson’s and Alzheimer’s, where mitochondrial dysfunction plays a role. Enables researchers to evaluate the effects of pharmacological agents, gene therapy, or lifestyle interventions on cellular energy regulation pathways.