Used in neuroscience and genetic disorder research to quantify levels of the Spatacsin protein in biological samples. Helps in studying hereditary spastic paraplegia, particularly SPG11-linked forms, by measuring protein expression in cell cultures, tissue lysates, or cerebrospinal fluid. Supports investigation into disease mechanisms, progression markers, and potential therapeutic interventions targeting neurodegeneration. Widely applied in academic labs, pharmaceutical research, and clinical studies focused on rare neurological diseases.