Used in biomedical research to quantify 26S proteasome levels in rat tissue samples or cell lysates. Helps study protein degradation pathways, particularly in models of neurodegenerative diseases, muscle atrophy, and aging. Enables researchers to assess proteasome activity changes under experimental conditions, such as drug treatment or oxidative stress. Commonly applied in preclinical studies to evaluate cellular protein homeostasis and monitor responses to therapeutic interventions targeting the ubiquitin-proteasome system.