Pure-Matrine™ (98%, from Sophora Flavescens Root Extract)

Pure-Matrine™ (98%, from Sophora Flavescens Root Extract)
Cosmetics Code: 125661

naturally occurring alkaloid found in the root of the Sophora flavescens plant, commonly used in traditional Chinese medicine. It has several potential topical benefits, including anti-inflammatory, anti-microbial, and anti-aging properties

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Matrine is a naturally occurring alkaloid found in the root of the Sophora flavescens plant, commonly used in traditional Chinese medicine. It has several potential topical benefits, including anti-inflammatory, anti-microbial, and anti-aging properties.

Topical Benefits of Matrine

  1. Anti-inflammatory Properties: Matrine has been shown to reduce inflammation by inhibiting the release of pro-inflammatory cytokines. This makes it potentially useful in treating inflammatory skin conditions like eczema, psoriasis, and acne.

    • Research Citation: Chen, T., Li, J., Cao, J., & Xu, Q. (2011). Matrine inhibits the expression of TNF-α and IL-6 in lipopolysaccharide-stimulated microglial cells through inhibition of NF-κB signaling pathway. International Immunopharmacology, 11(9), 1095-1102. DOI:10.1016/j.intimp.2011.03.012

  2. Anti-microbial Effects: Matrine has demonstrated activity against various bacteria and fungi, which could make it useful for treating skin infections or preventing acne.

    • Research Citation: Li, Y., Jiang, J., & Lu, X. (2015). Antimicrobial effect of matrine against Helicobacter pylori and its potential in clinical application. Phytotherapy Research, 29(11), 1678-1683. DOI:10.1002/ptr.5424

  3. Anti-aging Effects: Matrine can help reduce the appearance of wrinkles and improve skin elasticity by promoting collagen synthesis and inhibiting enzymes that break down collagen.

    • Research Citation: Wang, Z., Sun, G., Sun, Q., & Xia, Z. (2013). The effect of matrine on UV-induced matrix metalloproteinase expression in human dermal fibroblasts. Journal of Dermatological Science, 70(2), 141-146. DOI:10.1016/j.jdermsci.2013.02.006

Usage: Can be used in anti-irritation products.

How to mix: Mix in the formula in the last step, avoid heat.

Usage rate: 0.1%-1.0% (recommend 0.5%)

Product appearance: white to off-white powder

Solubility: Soluble in water

Storage: For long-term storage Store in the refrigerator. Avoid exposure to light or heat. Seal the lid tightly. Shelf life is at least 2 years.

INCI Name : Matrine


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Test Name Specification
Appearance White to yellowish powder; Odorless, bitter
Specific optical rotation +31 to +36 degree
pH 9.5-10.5
Chloride 0.01% Max
Loss on Drying 5% Max
Residue on ignition 0.1% Max
Heavy Metals (Pb) 20ppm Max
Arsenic 2ppm Max
Assay (on dry basis) 98% Min
Total plate count 100CFU/g Max
Mould and Yeast 20CFU/g Max
E. Coli Negative

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Pure-Matrine™ (98%, from Sophora Flavescens Root Extract)

naturally occurring alkaloid found in the root of the Sophora flavescens plant, commonly used in traditional Chinese medicine. It has several potential topical benefits, including anti-inflammatory, anti-microbial, and anti-aging properties

Matrine is a naturally occurring alkaloid found in the root of the Sophora flavescens plant, commonly used in traditional Chinese medicine. It has several potential topical benefits, including anti-inflammatory, anti-microbial, and anti-aging properties.

Topical Benefits of Matrine

  1. Anti-inflammatory Properties: Matrine has been shown to reduce inflammation by inhibiting the release of pro-inflammatory cytokines. This makes it potentially useful in treating inflammatory skin conditions like eczema, psoriasis, and acne.

    • Research Citation: Chen, T., Li, J., Cao, J., & Xu, Q. (2011). Matrine inhibits the expression of TNF-α and IL-6 in lipopolysaccharide-stimulated microglial cells through inhibition of NF-κB signaling pathway. International Immunopharmacology, 11(9), 1095-1102. DOI:10.1016/j.intimp.2011.03.012

  2. Anti-microbial Effects: Matrine has demonstrated activity against various bacteria and fungi, which could make it useful for treating skin infections or preventing acne.

    • Research Citation: Li, Y., Jiang, J., & Lu, X. (2015). Antimicrobial effect of matrine against Helicobacter pylori and its potential in clinical application. Phytotherapy Research, 29(11), 1678-1683. DOI:10.1002/ptr.5424

  3. Anti-aging Effects: Matrine can help reduce the appearance of wrinkles and improve skin elasticity by promoting collagen synthesis and inhibiting enzymes that break down collagen.

    • Research Citation: Wang, Z., Sun, G., Sun, Q., & Xia, Z. (2013). The effect of matrine on UV-induced matrix metalloproteinase expression in human dermal fibroblasts. Journal of Dermatological Science, 70(2), 141-146. DOI:10.1016/j.jdermsci.2013.02.006

Usage: Can be used in anti-irritation products.

How to mix: Mix in the formula in the last step, avoid heat.

Usage rate: 0.1%-1.0% (recommend 0.5%)

Product appearance: white to off-white powder

Solubility: Soluble in water

Storage: For long-term storage Store in the refrigerator. Avoid exposure to light or heat. Seal the lid tightly. Shelf life is at least 2 years.

INCI Name : Matrine

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