Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules where halogenated pyrazines enhance reactivity and binding properties. Its iodine functionality allows for further functionalization via cross-coupling reactions such as Suzuki or Heck couplings, making it valuable in medicinal chemistry for constructing complex heterocyclic systems. Also employed in materials science for the preparation of organic semiconductors and functional dyes due to its electron-deficient aromatic core.