4-Fluoro-3-(tributylstannyl)-1H-pyrazole
95%
Reagent
Code: #188376
CAS Number
853180-40-2
science Other reagents with same CAS 853180-40-2
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Molecular Information
Weight
375.11 g/mol
Formula
C₁₅H₂₉FN₂Sn
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Storage & Handling
Storage
2-8°C
description Product Description
Used primarily as an intermediate in organic synthesis, especially in cross-coupling reactions such as Stille coupling. It enables the introduction of fluorinated pyrazole structures into complex molecules, which are valuable in pharmaceutical and agrochemical development due to the metabolic stability and enhanced bioavailability imparted by the fluorine atom. The tributylstannyl group acts as a leaving group, facilitating carbon-carbon bond formation with aryl or vinyl halides under palladium catalysis. This compound is particularly useful in the preparation of bioactive heterocycles and fluorinated analogs in medicinal chemistry research.
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