1H-Pyrazole, 1-(3-oxetanylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
97%
Reagent
Code: #191274
CAS Number
1578484-07-7
science Other reagents with same CAS 1578484-07-7
blur_circular Chemical Specifications
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Molecular Information
Weight
264.13 g/mol
Formula
C₁₃H₂₁BN₂O₃
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Registry Numbers
MDL Number
MFCD28501270
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Physical Properties
Boiling Point
391.7±12.0 °C(Predicted)
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Storage & Handling
Density
1.18±0.1 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used primarily as a key intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to construct complex drug molecules. Its boronate ester group enables efficient carbon-carbon bond formation, making it valuable in the development of active pharmaceutical ingredients (APIs). The pyrazole ring with the oxetane methyl group enhances metabolic stability and solubility in drug candidates, often leveraged in medicinal chemistry for designing bioactive compounds. Commonly applied in research and development of kinase inhibitors and other targeted therapies.
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