8-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
98%
Reagent
Code: #142226
CAS Number
643067-83-8
blur_circular Chemical Specifications
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Molecular Information
Weight
216.03 g/mol
Formula
C₇H₆BrNO₂
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Registry Numbers
MDL Number
MFCD22394058
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Physical Properties
Boiling Point
291.2±40.0 °C(Predicted)
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Storage & Handling
Density
1.690±0.06 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and central nervous system agents. Its structure supports functionalization at multiple sites, making it valuable in medicinal chemistry for constructing bioactive molecules. Commonly employed in cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations to introduce aryl or amino groups. Also utilized in the preparation of selective receptor modulators due to its rigid, heterocyclic framework that enhances binding affinity and metabolic stability.
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