2-Chloro-3-((trimethylsilyl)ethynyl)pyridin-4-amine
97%
Reagent
Code: #163462
CAS Number
1138444-10-6
blur_circular Chemical Specifications
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Molecular Information
Weight
224.76 g/mol
Formula
C₁₀H₁₃ClN₂Si
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Registry Numbers
MDL Number
MFCD11857680
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Physical Properties
Boiling Point
328.0±42.0 °C(Predicted)
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Storage & Handling
Density
1.13±0.1 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for efficient coupling reactions in medicinal chemistry, enabling the introduction of pyridine-based scaffolds into larger bioactive molecules. The trimethylsilyl group enhances stability and selectivity during synthetic transformations, making it valuable in controlled cross-coupling processes. Commonly employed in research settings for designing targeted therapies involving tyrosine kinase and related signaling pathways.
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