1-Cyclopropyl-6-oxo-1,6-dihydropyridine-3-boronic Acid Pinacol Ester
98%
Reagent
Code: #192628
CAS Number
1596367-55-3
science Other reagents with same CAS 1596367-55-3
blur_circular Chemical Specifications
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Molecular Information
Weight
261.12 g/mol
Formula
C₁₄H₂₀BNO₃
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Registry Numbers
MDL Number
MFCD16996103
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Physical Properties
Boiling Point
326.6±52.0 °C(Predicted)
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Storage & Handling
Density
1.13±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biologically active compounds, particularly in pharmaceutical development. Its boronic ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in constructing complex heterocyclic systems. Commonly employed in the preparation of kinase inhibitors and other drug candidates where the pyridine scaffold is essential for target binding. The cyclopropyl group enhances metabolic stability and influences molecular conformation, contributing to improved potency and selectivity in final active compounds.
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