Used primarily as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its structure allows for selective functionalization in heterocyclic chemistry, making it valuable in the development of kinase inhibitors and other bioactive molecules. The iodo and aldehyde groups provide reactive sites for cross-coupling reactions, such as Suzuki or Heck reactions, enabling the construction of complex aromatic systems. Commonly employed in medicinal chemistry for lead optimization and in the preparation of nicotinamide-based analogs targeting metabolic and neurological disorders.