2-(5-Fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid
97%
Reagent
Code: #115293
CAS Number
56059-30-4
blur_circular Chemical Specifications
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Molecular Information
Weight
188.11 g/mol
Formula
C₆H₅FN₂O₄
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Registry Numbers
MDL Number
MFCD00832183
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Storage & Handling
Storage
Room temperature, dry and sealed
description Product Description
This compound is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of antiviral and anticancer agents. Its structure, featuring a fluorinated pyrimidine core, is particularly valuable in the development of nucleoside analogs, which are crucial for inhibiting viral replication and targeting cancer cells. Researchers leverage its properties to design prodrugs that can be metabolically activated within the body, enhancing therapeutic efficacy. Additionally, it is employed in biochemical studies to investigate enzyme mechanisms and interactions, particularly those involving thymidylate synthase, an enzyme critical for DNA synthesis. Its applications also extend to the development of diagnostic tools and imaging agents for detecting disease markers.
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