4-(tert-Butyl)-2-chloropyrimidine
98%
Reagent
Code: #145123
CAS Number
66522-06-3
blur_circular Chemical Specifications
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Molecular Information
Weight
170.64 g/mol
Formula
C₈H₁₁ClN₂
thermostat
Physical Properties
Boiling Point
261.5±9.0°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of herbicides and fungicides. The tert-butyl and chloro groups on the pyrimidine ring enhance stability and improve solubility in organic solvents, allowing for selective functionalization and making it valuable in building complex molecules in medicinal chemistry. Commonly employed in cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations to form carbon-carbon or carbon-nitrogen bonds. Also utilized in the preparation of kinase inhibitors and other biologically active compounds in research settings.
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