5-Chloro-2-(trifluoromethyl)pyrimidine
97%
Reagent
Code: #163969
CAS Number
845618-08-8
blur_circular Chemical Specifications
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Molecular Information
Weight
182.532 g/mol
Formula
C₅H₂ClF₃N₂
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Registry Numbers
MDL Number
MFCD09754045
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Physical Properties
Boiling Point
115.4±40.0 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of agrochemicals and pharmaceuticals, particularly in the development of herbicides and fungicides. Its structure allows for easy functionalization, making it valuable in medicinal chemistry for constructing pyrimidine-based bioactive molecules. It is also employed in the preparation of kinase inhibitors and other targeted therapies in drug discovery. Due to the electron-withdrawing nature of the chloro and trifluoromethyl groups, it participates effectively in cross-coupling reactions, enabling the formation of complex organic compounds in research and industrial settings.
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