5-Bromo-4-(trifluoromethyl)-2-pyrimidinamine
95%
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Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its structure allows for selective binding in biological systems, making it valuable in medicinal chemistry. It is also commonly used in palladium-catalyzed cross-coupling reactions, such as Suzuki coupling, to introduce aryl groups and create more complex derivatives for biological screening. Also employed in agrochemical research for designing novel pesticides with improved efficacy and environmental profiles. Commonly utilized in fluorescent probe development due to its ability to enhance signal detection in cellular imaging. Serves as a building block in combinatorial chemistry for high-throughput screening of bioactive molecules.
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