tert-Butyl (trans-4-fluoropyrrolidin-3-yl)carbamate
97%
Reagent
Code: #141089
CAS Number
186201-09-2
blur_circular Chemical Specifications
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Molecular Information
Weight
204.2412 g/mol
Formula
C₉H₁₇FN₂O₂
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Registry Numbers
MDL Number
MFCD18791661
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Physical Properties
Boiling Point
295.3±40.0 °C(Predicted)
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Storage & Handling
Density
1.10±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of biologically active molecules targeting central nervous system disorders. Its structure incorporates a protected amine and a fluorinated pyrrolidine ring, making it valuable for medicinal chemistry efforts focused on enhancing metabolic stability and binding affinity. Commonly employed in the preparation of enzyme inhibitors and receptor modulators, especially in projects involving fluorine scanning to optimize pharmacokinetic properties. The tert-butyl carbamate group allows for selective deprotection, enabling further functionalization in multi-step synthetic routes.
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