trans-1-(tert-butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid
98%
Reagent
Code: #145769
CAS Number
169248-97-9
blur_circular Chemical Specifications
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Molecular Information
Weight
359.35 g/mol
Formula
C₁₇H₂₀F₃NO₄
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Registry Numbers
MDL Number
MFCD06659291
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Physical Properties
Boiling Point
434.7°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structure supports the modulation of receptor activity, making it valuable in medicinal chemistry for creating analogs with enhanced selectivity and metabolic stability. Commonly employed in the preparation of protease inhibitors and receptor antagonists due to the conformational rigidity provided by the pyrrolidine core and the electron-withdrawing effect of the trifluoromethyl group. Also utilized in structure-activity relationship (SAR) studies to optimize drug candidates.
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