tert-Butyl 3-iodopyrrolidine-1-carboxylate
95%
Reagent
Code: #148381
CAS Number
774234-25-2
blur_circular Chemical Specifications
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Molecular Information
Weight
297.13 g/mol
Formula
C₉H₁₆INO₂
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Registry Numbers
MDL Number
MFCD12031283
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Physical Properties
Boiling Point
300.7±35.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry and sealed from light
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules and drug candidates. The iodine substituent allows for further functionalization via cross-coupling reactions such as Suzuki or Heck couplings, enabling the construction of complex organic structures. The tert-butyl carbamate (Boc) protecting group stabilizes the pyrrolidine nitrogen during multi-step syntheses and can be easily removed under mild acidic conditions when needed. Commonly employed in the preparation of nitrogen-containing heterocycles and peptidomimetics, especially in research targeting central nervous system agents and enzyme inhibitors.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Pale-yellow to Yellow-brown Liquid to Sticky Oil to Semi-Solid |
| Purity | 94.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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