tert-Butyl 3-(tosyloxy)pyrrolidine-1-carboxylate
95%
Reagent
Code: #150937
CAS Number
103057-45-0
blur_circular Chemical Specifications
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Molecular Information
Weight
341.42 g/mol
Formula
C₁₆H₂₃NO₅S
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Registry Numbers
MDL Number
MFCD07787191
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Physical Properties
Melting Point
77-79 °C
Boiling Point
461.9±38.0 °C(Predicted)
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Storage & Handling
Density
1.25±0.1 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the preparation of bioactive pyrrolidine-containing compounds. Its protected amine group and activated hydroxyl function allow selective transformations in multi-step organic syntheses. Commonly employed in the development of protease inhibitors and central nervous system agents. The tosylate group serves as a good leaving group, enabling nucleophilic substitution reactions, while the tert-butoxycarbonyl (Boc) group provides amine protection under various reaction conditions.
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