1-Boc-2-chloromethyl-pyrrolidine
97%
Reagent
Code: #152464
CAS Number
1142400-61-0
blur_circular Chemical Specifications
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Molecular Information
Weight
219.708 g/mol
Formula
C₁₀H₁₈ClNO₂
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Registry Numbers
MDL Number
MFCD18837085
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Physical Properties
Boiling Point
284 °C at 760 mmHg
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Storage & Handling
Density
1.101 g/cm3
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where the Boc-protected pyrrolidine scaffold is required. The chloromethyl group allows for further alkylation or functionalization, enabling the construction of complex nitrogen-containing heterocycles. Commonly employed in medicinal chemistry for drug discovery programs targeting central nervous system agents, enzyme inhibitors, and receptor modulators. Its protected amine group ensures selective reactivity, making it valuable in multi-step organic syntheses.
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