tert-ButylN-(3-cyanopyrrolidin-3-yl)carbamate
98%
Reagent
Code: #155003
CAS Number
1205749-53-6
blur_circular Chemical Specifications
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Molecular Information
Weight
211.26 g/mol
Formula
C₁₀H₁₇N₃O₂
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Registry Numbers
MDL Number
MFCD14582457
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Storage & Handling
Storage
2-8°C
description Product Description
tert-Butyl N-(3-cyanopyrrolidin-3-yl)carbamate serves as a protected intermediate in the synthesis of biologically active pharmaceutical compounds, notably DPP-4 inhibitors like saxagliptin in the gliptin class for treating type 2 diabetes by regulating blood glucose levels. The Boc carbamate group protects the amino functionality during multi-step synthesis, preventing side reactions, and is readily deprotected at the end. The cyano group on the pyrrolidine ring enables additional modifications, supporting the creation of targeted enzyme inhibitors. This compound is widely used in medicinal chemistry research for diabetes therapeutics and related drug discovery programs.
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