7-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine
≥95%
Reagent
Code: #120805
CAS Number
768350-54-5
blur_circular Chemical Specifications
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Molecular Information
Weight
454.29 g/mol
Formula
C₂₂H₁₇BrFN₃O₂
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Registry Numbers
MDL Number
MFCD19440903
thermostat
Physical Properties
Boiling Point
541.094°C at 760 mmHg
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Storage & Handling
Storage
Room temperature, away from light, stored in an inert gas
description Product Description
This compound is primarily utilized in the field of medicinal chemistry and drug development. It serves as a key intermediate in the synthesis of targeted therapeutic agents, particularly in the development of kinase inhibitors. Kinase inhibitors are crucial in treating various types of cancers, as they block specific enzymes involved in the growth and proliferation of cancer cells. The structural features of this compound, including the quinazoline core and substituted aromatic rings, make it a valuable scaffold for designing molecules that can selectively inhibit tyrosine kinases or other related enzymes. Researchers often modify and optimize this compound to enhance its binding affinity, selectivity, and pharmacokinetic properties, aiming to create effective and safe drugs for oncology applications. Additionally, its bromo and fluoro substituents provide reactive sites for further chemical modifications, enabling the exploration of diverse derivatives with potential biological activity.
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7-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine
This compound is primarily utilized in the field of medicinal chemistry and drug development. It serves as a key intermediate in the synthesis of targeted therapeutic agents, particularly in the development of kinase inhibitors. Kinase inhibitors are crucial in treating various types of cancers, as they block specific enzymes involved in the growth and proliferation of cancer cells. The structural features of this compound, including the quinazoline core and substituted aromatic rings, make it a valuable scaffold for designing molecules that can selectively inhibit tyrosine kinases or other related enzymes. Researchers often modify and optimize this compound to enhance its binding affinity, selectivity, and pharmacokinetic properties, aiming to create effective and safe drugs for oncology applications. Additionally, its bromo and fluoro substituents provide reactive sites for further chemical modifications, enabling the exploration of diverse derivatives with potential biological activity.
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