4-Chloro-6-iodo-7-methoxy-quinazoline
97%
Reagent
Code: #163089
CAS Number
1172851-61-4
blur_circular Chemical Specifications
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Molecular Information
Weight
320.51 g/mol
Formula
C₉H₆ClIN₂O
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Registry Numbers
MDL Number
MFCD12973651
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in the development of anticancer agents. Its structure allows for selective substitution at multiple sites, making it valuable in pharmaceutical research for targeting epidermal growth factor receptor (EGFR) pathways. Commonly employed in the preparation of compounds with activity against solid tumors, including non-small cell lung cancer. Also utilized in medicinal chemistry for building blocks in kinase inhibitor scaffolds due to its reactivity and stability in cross-coupling reactions.
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