1-(4-((3-Chloro-4-Fluorophenyl)Amino)-7-Methoxyquinazolin-6-Yl)-5-Hydroxypyrrolidin-2-One
98%
Reagent
Code: #165664
CAS Number
2190490-31-2
blur_circular Chemical Specifications
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Molecular Information
Weight
402.81 g/mol
Formula
C₁₉H₁₆ClFN₄O₃
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Storage & Handling
Storage
Room temperature
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly those targeting epidermal growth factor receptor (EGFR) pathways. It plays a role in the development of anticancer agents, especially for treating non-small cell lung cancer and other solid tumors. Its structure enables selective inhibition of mutant forms of EGFR, improving therapeutic efficacy while reducing side effects. Also investigated for use in targeted cancer therapies due to its ability to cross cell membranes and bind irreversibly to kinase domains.
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