tert-Butyl 6-bromo-3,4-dihydroquinoline-1(2H)-carboxylate
97%
Reagent
Code: #148502
CAS Number
1123169-45-8
blur_circular Chemical Specifications
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Molecular Information
Weight
312.20 g/mol
Formula
C₁₄H₁₈BrNO₂
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Registry Numbers
MDL Number
MFCD11858570
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Storage & Handling
Storage
Room temperature, dry seal
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structure allows for selective functionalization at the bromo position, enabling coupling reactions such as Suzuki or Buchwald-Hartwig aminations to build complex heterocyclic systems. The tert-butyl carbamate (Boc) group provides protection for the secondary amine during multi-step syntheses, ensuring stability and chemoselectivity. Commonly employed in medicinal chemistry for constructing dihydroquinoline-based scaffolds found in receptor agonists and enzyme inhibitors.
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