6-Bromo-4-chloro-8-fluoroquinoline-3-carbonitrile
98%
Reagent
Code: #156446
CAS Number
886362-71-6
blur_circular Chemical Specifications
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Molecular Information
Weight
285.5 g/mol
Formula
C₁₀H₃BrClFN₂
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Registry Numbers
MDL Number
MFCD06796582
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of fluorinated quinoline-based pharmaceuticals, particularly in the development of kinase inhibitors and antiviral agents. Its halogenated structure allows for selective cross-coupling reactions, enabling the construction of complex bioactive molecules. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the electron-withdrawing groups and nitrile functionality that enhance binding affinity and metabolic stability. Also utilized in the preparation of fluorescent probes and materials for organic electronics where quinoline derivatives serve as electron-transport components.
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