4-Chloro-7-(trifluoromethyl)quinoline
97%
Reagent
Code: #160835
CAS Number
346-55-4
blur_circular Chemical Specifications
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Molecular Information
Weight
231.6 g/mol
Formula
C₁₀H₅ClF₃N
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Registry Numbers
MDL Number
MFCD00006775
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Physical Properties
Melting Point
69-71°C(lit.)
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in antimalarial drugs. It serves as a building block in the development of kinase inhibitors for cancer therapy due to its ability to enhance binding affinity and metabolic stability. Also employed in agrochemicals for crop protection agents, leveraging its electron-withdrawing properties to improve bioavailability and environmental persistence. Its trifluoromethyl and chloro substituents make it valuable in medicinal chemistry for optimizing lipophilicity and target selectivity.
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