Gatifloxacin hydrate is widely used as an antibiotic in the treatment of various bacterial infections. It is particularly effective against respiratory tract infections, including bronchitis and pneumonia, due to its broad-spectrum activity against both Gram-positive and Gram-negative bacteria. In ophthalmology, it is applied as an eye drop to treat bacterial conjunctivitis and corneal ulcers, offering quick relief and reducing the risk of complications. Additionally, it is utilized in managing urinary tract infections and skin infections, where its potent antibacterial properties help in eradicating the causative pathogens. The hydrate form ensures better stability and solubility, enhancing its efficacy in various formulations. Its use is guided by susceptibility testing to ensure targeted and effective treatment.