Used in immunological research to study natural killer (NK) cell regulation and T cell responses. Binds to HLA-E molecules on target cells, modulating immune activity. Commonly applied in receptor-ligand interaction studies, immunoassays, and flow cytometry to detect and quantify NKG2A expression. Also utilized in therapeutic development for cancer immunotherapy, where blocking NKG2A enhances NK and T cell-mediated killing of tumor cells. Supports the development of monoclonal antibodies and checkpoint inhibitors.