huCD226-HEK293 is not a chemical but a biological reagent, specifically a recombinant protein or cell line expressing human CD226 (DNAM-1) produced in HEK293 cells. It is primarily used in immunological research to study immune cell activation and signaling pathways. The protein plays a key role in T cell and natural killer (NK) cell-mediated immune responses by binding to ligands such as PVR (CD155) and Nectin-2 (CD112) on target cells. This reagent is widely applied in binding assays, functional studies, and high-throughput screening to evaluate interactions between CD226 and its ligands or to test blocking antibodies and therapeutic candidates. It supports the development of immunotherapies, especially in oncology, where modulating CD226 activity can enhance anti-tumor immunity. Additionally, it is used in quality control and validation of antibodies, flow cytometry, and ELISA protocols.