This recombinant protein is primarily used in immunological research to study immune cell interactions, particularly in the context of natural killer (NK) cell and T cell regulation. It serves as a tool to investigate the CD96 pathway, which plays a role in modulating immune responses by interacting with ligands such as CD155 expressed on tumor cells and antigen-presenting cells. Due to its expression in CHO-S cells with a muCD96 (mouse) sequence, it is suitable for in vitro binding assays, blocking studies, and receptor-ligand interaction analyses. It is also employed in cancer immunotherapy research to understand checkpoint mechanisms and to develop potential therapeutic strategies that enhance immune surveillance. Its soluble form allows for flexible use in functional assays and protein characterization.