This recombinant protein is primarily used in immunological research to study the signaling pathways associated with interleukin-18 (IL-18), a pro-inflammatory cytokine. It serves as a soluble receptor decoy that can modulate IL-18-mediated immune responses, making it valuable in experiments focused on inflammation, autoimmune diseases, and cancer immunotherapy. Due to its chimeric structure with a CHO-K1 cell-derived glycosylation pattern, it exhibits enhanced stability and binding affinity, which supports its use in cell culture assays and in vivo models. It is also employed in the development and validation of anti-inflammatory therapeutics and diagnostic tools targeting the IL-18 pathway.