Used in research to study interleukin-4 receptor signaling pathways, particularly in immune response regulation. Helps in understanding allergic reactions, asthma, and autoimmune diseases. Employed in protein interaction studies and antibody development due to its soluble receptor form. Commonly used in ELISA, flow cytometry, and binding assays to evaluate drug candidates targeting IL-4 and IL-13 pathways. Supports development of biologics by providing a human-relevant model for receptor-ligand interactions.