Aliskiren Hemifumarate
10mM in DMSO
Reagent
Code: #134274
CAS Number
173334-58-2
blur_circular Chemical Specifications
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Molecular Information
Weight
551.76 g/mol
Formula
C₃₀H₅₃N₃O₆
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Registry Numbers
MDL Number
MFCD10566724
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of hypertension (high blood pressure). It works by directly inhibiting renin, an enzyme involved in the regulation of blood pressure through the renin-angiotensin-aldosterone system (RAAS). By blocking renin, it reduces the production of angiotensin I and subsequently angiotensin II, a potent vasoconstrictor, leading to relaxation of blood vessels and lower blood pressure. It is prescribed as a monotherapy or in combination with other antihypertensive agents when blood pressure is not adequately controlled. Its use may reduce the risk of cardiovascular events associated with chronic high blood pressure. Not typically used in patients with severe renal impairment or those on dual RAAS blockade due to increased risk of adverse effects.
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