Flugestone is primarily used in veterinary medicine, particularly in the management of reproductive cycles in livestock. It is commonly employed to synchronize estrus in cattle, sheep, and goats, ensuring that multiple animals come into heat simultaneously. This synchronization facilitates timed artificial insemination, improving breeding efficiency and herd management. In addition, it is used to treat certain reproductive disorders, such as irregular estrous cycles or anestrus, helping to restore normal fertility. Its application is crucial in optimizing reproductive performance and enhancing the productivity of livestock operations.