Adarotene is primarily used in dermatology for the treatment of skin conditions. It is effective in managing acne vulgaris by reducing inflammation and preventing the formation of new comedones. Additionally, it is utilized in the treatment of psoriasis to help normalize skin cell growth and reduce scaling and redness. Adarotene is also being researched for its potential in treating certain types of skin cancer due to its ability to regulate cell proliferation and differentiation. Its application typically involves topical use, ensuring targeted action with minimal systemic absorption.