Rhenium(V) chloride is primarily used as a catalyst in industrial chemical processes, particularly for alkene isomerization and certain alkylation reactions. It exhibits high activity in promoting carbon-carbon bond formation and is effective in select hydrogenation and dehydrogenation processes. Additionally, it serves as a key precursor in research for synthesizing rhenium-based organometallic complexes and materials with unique catalytic or electronic properties. Its versatility makes it essential for developing advanced organometallic compounds applied in fine chemicals, pharmaceuticals, and materials science.