SR-3677 is primarily used in research settings as a potent and selective inhibitor of ROCK (Rho-associated protein kinase). Its application is significant in studying cellular processes such as cytoskeleton organization, cell migration, and smooth muscle contraction. Researchers utilize SR-3677 to investigate its effects on conditions like hypertension, glaucoma, and cancer metastasis, as ROCK signaling plays a crucial role in these diseases. Additionally, it is employed in neuroscience studies to explore its potential in treating neurodegenerative disorders by modulating neuronal cell survival and regeneration. Its specificity and efficacy make it a valuable tool for understanding ROCK-mediated pathways and developing therapeutic strategies.