Agarose Gel Loading Buffer-Ficoll is primarily used in molecular biology for the preparation and loading of DNA samples into agarose gels during electrophoresis. The Ficoll component increases the density of the sample, ensuring it sinks properly into the wells of the gel. This buffer also contains tracking dyes, which migrate alongside the DNA, allowing researchers to monitor the progress of the electrophoresis. It is particularly useful for applications requiring high-resolution separation of DNA fragments, such as in genetic analysis, cloning, and PCR product verification. The buffer helps maintain sample integrity and ensures accurate visualization of DNA bands under UV light after staining.