Rotundine is primarily used in the field of medicine due to its sedative and analgesic properties. It is commonly employed to alleviate symptoms of anxiety and insomnia, helping to induce relaxation and improve sleep quality. Additionally, it is utilized as a pain reliever for mild to moderate pain, particularly in cases of headaches or muscle discomfort. Rotundine is also studied for its potential role in managing certain neurological conditions, as it may help regulate neurotransmitter activity in the brain. Its natural origin makes it a preferred choice in traditional and alternative medicine practices for promoting calmness and reducing stress.