Ospemifene is primarily used in the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, which often occurs in postmenopausal women. It works by acting as an estrogen agonist/antagonist, helping to restore the vaginal lining and reduce discomfort during sexual intercourse. This medication is particularly beneficial for women who cannot or prefer not to use vaginal estrogen therapy. Additionally, it may improve vaginal dryness and other related symptoms, enhancing overall quality of life. Ospemifene is taken orally, making it a convenient option for long-term management of these conditions.